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Exploring the practices, challenges, and pathways for enhancement of grassroots social organizations in preventing child unintentional injuries: a qualitative study in Guizhou, China

Abstract: Children’s unintentional injuries represent a global public health problem. Guizhou, as an economically underdeveloped province in southwest China, faces challenges in…

Date: 2026-01-29

Identification of maturity-onset diabetes of the young through targeted next-generation sequencing in Thai patients with atypical diabetes in real-world practice

Abstract: Maturity-onset diabetes of the young (MODY) is often misdiagnosed as either autoimmune type 1 diabetes (T1D) or polygenic type 2 diabetes (T2D), resulting in missed…

Date: 2026-01-29

Long-term health effects of COVID-19 among patients in Croatian primary care settings

Abstract: The COVID-19 pandemic has left lasting effects that extend beyond the acute phase of infection, with increasing evidence of long-term health consequences. This study…

Date: 2026-01-29

The prognostic significance of JAML and its role in remodeling the immune microenvironment via the cGAS-STING pathway in endometrial cancer

Abstract: Endometrial cancer (EC) is a major gynecological malignancy with a poor prognosis in the advanced stages. Junctional adhesion molecule-like protein (JAML) is gaining…

Date: 2026-01-29

Real-world data-based assessment of therapy-related myeloid neoplasms after poly(ADP-ribose) polymerase inhibitor treatment in ovarian cancer

Abstract: Poly(ADP-ribose) polymerase inhibitors (PARPi) have significantly improved outcomes in ovarian cancer. However, therapy-related myeloid neoplasms (t-MNs) have emerged as…

Date: 2026-01-29

tsRNA-Ala-3–0030 drives ovarian cancer progression by suppressing ZNF70

Abstract: Globally, ovarian cancer remains a leading cause of gynecologic cancer death. This poor prognosis is primarily attributed to advanced disease at diagnosis, a high…

Date: 2026-01-29

Optimizing mature oocyte yield in IVF: clinical comparison of r-hFSH+r-hLH and HMG in women with a stimulation dosage of at least 300 IU of gonadotropins

Abstract: To study the impact of luteinizing hormone (LH) in stimulation medication on the mature oocyte yield obtained in in women receiving ovarian stimulation (OS) with a…

Date: 2026-01-29

Impact of low-dose sufentanil on the effective sedative dose of ciprofol for BIS-guided induction in elderly patients: an up-and-down sequential allocation trial

Abstract: This study aimed to evaluate the effect of a single low dose of sufentanil on the effective dose of ciprofol required to achieve a bispectral index (BIS)

Date: 2026-01-29

The therapeutic potential of ayahuasca in depression, generalized anxiety, and substance use disorders: modulation of the depressive burden in a longitudinal study

Abstract: This longitudinal observational study evaluated changes in depressive symptoms associated with ritualistic ayahuasca use in patients diagnosed with depressive disorders,…

Date: 2026-01-29

CD4 + T cell dysregulation in major depressive disorder is associated with sleep disturbance

Abstract: Emerging evidence supports the role of immune-mediated neuroinflammatory processes and disrupted sleep patterns in elevating susceptibility to major depressive disorder…

Date: 2026-01-29