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Prevalence and clinical relevance of corneal astigmatism in cataract surgery candidates: a southern Italian cohort study

Abstract: Corneal astigmatism is a major determinant of visual outcomes after cataract surgery, and its accurate preoperative characterization is essential for surgical planning…

Date: 2026-01-21

Knowledge, attitudes, and practices of cataract patients in Shenzhen regarding cataract treatment

Abstract: This study aimed to explore knowledge, attitudes, and practices (KAP) regarding cataracts among patients in Shenzhen. A cross-sectional study was conducted between 1…

Date: 2026-01-21

The association between triglyceride glucose-waist-to-height ratio and non-alcoholic fatty liver disease in adults aged over 60 in the United States: a cross-sectional study

Abstract: To identify the optimal surrogate indicator for the initial public health screening of non-alcoholic fatty liver disease (NAFLD) among U.S. adults aged 60 years and…

Date: 2026-01-21

Beyond traditional—the sick cirrhosis patient scores integrating cytokine and immune profiling for precision prognosis in hospitalized cirrhosis patients may help predict infection, ICU admission and long-term death post hospitalization

Abstract: Inflammatory biomarkers and immune cell function may provide prognostic value beyond traditional severity scores in hospitalized cirrhosis patients. We aimed to…

Date: 2026-01-21

MRGPRX2-expressing mast cells are increased in the GI tract of individuals with active inflammatory bowel disease and hereditary ?-tryptasemia

Abstract: Hereditary ?-tryptasemia (H?T), defined by increased TPSAB1 copy number and elevated basal serum tryptase, is associated with mast cell (MC)–mediated symptoms. However,…

Date: 2026-01-21

Pro-inflammatory dietary patterns and their association with cardiovascular disease and pancreatic cancer in a hospital population: a cross-sectional study

Abstract: To examine whether a concise, clinic-feasible Patient Inflammatory Diet Score (PIDS) relates to prevalent pancreatic cancer and cardiovascular disease (CVD) in a…

Date: 2026-01-21

Real-world use of efgartigimod in acetylcholine receptor antibody–positive generalized myasthenia gravis: experience from two centers in Greece and Cyprus

Abstract: Efgartigimod, an FcRn antagonist that reduces circulating immunoglobulin G (IgG), is approved for the treatment of acetylcholine receptor (AChR) antibody–positive…

Date: 2026-01-21

The impact of STING signaling on myeloid cells highlights macrophages as the major player in controlling Brucella abortus

Abstract: Brucellosis, caused by Brucella abortus ( Ba ), is one of the most common zoonoses worldwide. Some components of the bacteria can be recognized by the innate immune…

Date: 2026-01-21

Immunogenicity and protection mediated by dmLT and alum adjuvants for an HIV-1 vaccine

Abstract: The development of an effective HIV-1 vaccine is of paramount importance to global health. Here, we compared the influence of two adjuvants, Escherichia coli…

Date: 2026-01-21

Dupilumab treatment is not associated with changes in lymphoma risk in atopic dermatitis and other type 2 inflammatory diseases: data from a large-scale retrospective cohort study

Abstract: The association between atopic dermatitis (AD) and lymphoma risk remains inconclusive. Dupilumab, approved for moderate-to-severe AD, has been linked to an increased…

Date: 2026-01-20