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Development and internal-external validation of a machine learning-based risk prediction model for multidrug resistance in mechanically ventilated ICU patients with chronic obstructive pulmonary disease

Abstract: This study aimed to develop and conduct internal-external validation of a machine learning-based risk prediction model for multidrug-resistant (MDR) infection in…

Date: 2026-08-20

A preliminary analysis of the psychometric properties of the German O*NET interest profiler short form in rehabilitation education

Abstract: Interest is a key driver of performances, decisions and choices, for example starting an educational program. The German O*NET Interest Profiler Short Form is a recent…

Date: 2026-08-20

Early C-reactive protein kinetics predict outcomes in unresectable hepatocellular carcinoma treated with immune checkpoint inhibitors: a multicenter, observational study comparing different C-reactive protein kinetic definitions

Abstract: Immune checkpoint inhibitors (ICIs) have become the standard therapy for unresectable hepatocellular carcinoma (HCC). However, reliable prognostic biomarkers for…

Date: 2026-08-20

Integrated single-cell transcriptomic and machine-learning analyses identify a CD36-associated macrophage state in diabetic nephropathy

Abstract: Diabetic nephropathy (DN) is the leading cause of end-stage renal disease worldwide and is characterized by progressive glomerulosclerosis, tubulointerstitial fibrosis,…

Date: 2026-08-20

A nomogram prediction model for perioperative heart failure in elderly patients with intertrochanteric femoral fracture based on lasso-logistic regression

Abstract: To explore a nomogram prediction model for perioperative heart failure (HF) in elderly patients with intertrochanteric femoral fracture (ITF) based on Lasso-Logistic…

Date: 2026-08-20

Diagnostic performance of 3T MRI preoperative localization of parathyroid adenomas in primary hyperparathyroidism

Abstract: Preoperative localization is essential for the surgical management of primary hyperparathyroidism (PHPT). Ultrasound and 99mTc-sestamibi SPECT/CT are first-line imaging…

Date: 2026-08-20

Development and internal validation of a nomogram and machine-learning models for postoperative recurrence in adult patients with chronic rhinosinusitis with nasal polyps

Abstract: Practical preoperative tools for estimating postoperative recurrence in chronic rhinosinusitis with nasal polyps (CRSwNP) remain limited. We developed and internally…

Date: 2026-08-20

Infertile women's experience of stressful dilemmas during assisted reproductive technology treatment

Abstract: This study aimed to explore the unique stress experiences and multidimensional stress dilemmas of infertile women during assisted reproductive technology (ART) treatment…

Date: 2026-08-20

Associations among subjective cognitive complaints, perceived social support, and medication adherence in patients with psychotic disorders

Abstract: Medication adherence is essential for the management of psychotic disorders, yet it remains difficult for many patients to sustain over time. In this study, the focus is…

Date: 2026-08-20

Napping improves interhemispheric functional coordination during night shifts in nurses: analysis of voxel-mirrored homotopic connectivity

Abstract: Napping has been shown to improve cognitive performance in nurses working night shifts; however, the underlying mechanisms remain poorly understood. This study aims to…

Date: 2026-08-20