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Dynamics of immune-checkpoint regulators and inflammatory cytokines and chemokines associated with preterm birth before and after cervical cerclage

Abstract: Cervical insufficiency (CI), characterized by painless cervical dilation during the second trimester, is a major cause of preterm birth. However, the local…

Date: 2026-06-23

Immune activation induced by FOLR2 + decidual macrophage deficiency impairs decidualization and angiogenesis in spontaneous abortion

Abstract: Decidual macrophages maintain immune tolerance and support decidualization at the maternal–fetal interface. However, the heterogeneity and functions of macrophage…

Date: 2026-06-23

Biphasic tissue expression of cfa-miR-409-3p and cfa-miR-4270 during malignant transformation in canine mammary tumors: an exploratory study

Abstract: Canine mammary tumors (CMTs) are the most common malignancy in intact female dogs and represent a well-established spontaneous model for human breast cancer. MicroRNAs…

Date: 2026-06-23

Intraoperative desaturation in pediatric patients at high altitude: incidence, risk factors, and a non-linear body weight safety threshold

Abstract: Pediatric patients undergoing general anesthesia are vulnerable to intraoperative hypoxemia, and this risk may be magnified at high altitude. However, the specific…

Date: 2026-06-23

Trajectory models of serum creatinine and 28-day mortality in critically ill patients with sepsis complicated by type 2 diabetes mellitus: a cohort study

Abstract: In critically ill patients with sepsis complicated by type 2 diabetes mellitus (T2DM), renal dysfunction is prevalent; however, the association between dynamic serum…

Date: 2026-06-23

Teleophthalmology for triage and management of corneal pathologies at vision centres: a prospective observational service evaluation study in north India

Abstract: To assess the feasibility of teleophthalmology for triage and management of corneal diseases at vision centres (VCs) in rural and semi-urban North India. All patients…

Date: 2026-06-23

Identification and experimental validation of CD74, PGLYRP1, and TXN as potential biomarkers in rheumatoid arthritis: an integrative bulk and ScRNA-seq study

Abstract: Chronic joint inflammation, the hallmark of rheumatoid arthritis (RA), is an autoimmune condition that commonly leads to progressive joint damage and dysfunction. While…

Date: 2026-06-23

Comparative study on the efficacy of conservative treatment and surgical treatment for simple Mason II radial head fracture

Abstract: This study aimed to analyze the therapeutic effects of conservative fixation with braces vs. open reduction with internal fixation surgery for simple Mason II radial…

Date: 2026-06-23

Clinical outcomes after single-level posterior lumbar interbody fusion in osteoporotic patients with or without paraspinal muscle atrophy: a retrospective study

Abstract: Lumbar disc herniation (LDH) is a major cause of low back pain and disability. In osteoporotic patients undergoing posterior lumbar interbody fusion (PLIF),…

Date: 2026-06-23

Divergent risk profiles for cause-specific mortality in MASLD and MetALD: a nationwide population-based study

Abstract: Metabolic-dysfunction-associated steatotic liver disease (MASLD) and MASLD with increased alcohol intake (MetALD) are overlapping but distinct conditions that influence…

Date: 2026-06-23