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Integrative skin–blood transcriptomic analysis identifies circulating biomarkers reflecting disease activity in atopic dermatitis

Abstract: Atopic dermatitis (AD) is characterized by complex immune dysregulation primarily studied in lesional skin. Identifying circulating molecular signatures that mirror…

Date: 2026-06-09

Profound immune suppression and exhaustion characterize refractory mycoplasma pneumoniae pneumonia in children

Abstract: The mechanisms underlying refractory Mycoplasma pneumoniae ( M. pneumoniae ) pneumonia (RMPP) and its association with adaptive immune dysfunction remain incompletely…

Date: 2026-06-09

Modified Pemberton osteotomy for developmental dysplasia of the hip in children: a mid- to long-term follow-up study

Abstract: Developmental dysplasia of the hip (DDH) is a common pediatric condition requiring timely surgical intervention in older children. Conventional Pemberton osteotomy,…

Date: 2026-06-09

Different injection speeds produce distinct temporal dynamics of optic nerve sheath diameter increase during caudal block in children: a prospective randomized trial

Abstract: Caudal block increases optic nerve sheath diameter (ONSD), but its temporal dynamics vary considerably across centers. Injection speed is one of the unstandardized…

Date: 2026-06-09

Clinical correlation between platelet parameters and coronary artery lesions in pediatric Kawasaki disease

Abstract: To investigate the clinical correlation between the occurrence of coronary artery lesions and platelet levels in children with Kawasaki disease. Propensity score…

Date: 2026-06-09

Vitamin D status at birth among pregnant women and their newborns in Jordan: a cross-sectional study

Abstract: Growing evidence suggests a link between vitamin D deficiency during pregnancy and an increased risk of adverse pregnancy and birth outcomes. This study aimed to measure…

Date: 2026-06-09

Changes in ambient environmental conditions correspond to variations in in vitro fertilization outcomes during the COVID-19 pandemic

Abstract: Air pollution is associated with impaired oocyte and embryo development, but the modifying effects of large-scale societal disruptions remain unclear. The aim of this…

Date: 2026-06-09

Distinct immune responses to HIV and CMV in Hofbauer cells across gestation highlight evolving placental immune dynamics

Abstract: Hofbauer cells are fetal macrophages in the placental villous core that contribute to maternal–fetal tolerance and antiviral defense, but how their immune programs…

Date: 2026-06-09

Analysis of factors that increase serum progesterone levels on the day of hCG administration in gonadotropin-releasing hormone antagonist cycles

Abstract: To explore the factors associated with elevated serum progesterone (P) levels on the day of hCG administration in patients undergoing controlled ovarian stimulation…

Date: 2026-06-09

Efficacy and safety of Oliceridine versus Sufentanil in postoperative analgesia for burn skin grafting: a machine learning and SHAP-based cohort study

Abstract: Balancing profound analgesia with the minimization of opioid-related adverse events, particularly postoperative nausea and vomiting (PONV), remains challenging in burn…

Date: 2026-06-09