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Efficacy and safety of oliceridine in daytime hysteroscopic polypectomy: a randomized, double-blind, single-center controlled trial

Abstract: This study aimed to compare the effects of oliceridine, fentanyl, and sufentanil on early recovery and perioperative safety during hysteroscopic polypectomy. A…

Date: 2026-05-22

Questionnaire on efficacy of the competency-oriented integrated residency and fellowship training for ophthalmologists in Shanghai

Abstract: The integrated resident and fellowship (IRF) training represents a pivotal direction in China’s medical education reform, however, there are few reports detailing its…

Date: 2026-05-22

Validation and clinical utility of OMGRate and MG-QOL15 in evaluating symptoms and quality of life in Chinese patients with ocular myasthenia gravis

Abstract: This study aimed to evaluate the value of the OMGRate and MG-QOL 15 in assessing quality of life (QoL) before and after treatment in ocular myasthenia gravis (OMG) and…

Date: 2026-05-22

Age-related changes in central corneal thickness and their association with ocular biometric parameters in children

Abstract: To investigate age-related changes in central corneal thickness (CCT) and its relationship with ocular biometric parameters in children. This retrospective study…

Date: 2026-05-22

Single-cell extracellular vesicle-program scoring maps immunometabolic rewiring and immune crosstalk of mesenchymal stromal cells in intervertebral disc degeneration, prioritizing AP2S1 and CSTB

Abstract: Intervertebral disc degeneration (IDD) is increasingly viewed as an immune-perturbed and metabolically stressed niche rather than a purely mechanical or aging-related…

Date: 2026-05-22

Laboratory biomarkers and radiographic osteolysis after total knee arthroplasty: a retrospective pilot study

Abstract: This study aimed to identify early risk factors for periprosthetic osteolysis after total knee arthroplasty (TKA) and establish clinically useful predictive biomarkers.…

Date: 2026-05-22

GPX7 marks fibroblast-associated stromal–innate immune crosstalk in ulcerative colitis

Abstract: Ulcerative colitis is sustained by stromal remodeling and innate immune activation. Whether serine-glycine-one-carbon metabolism contributes to fibroblast–macrophage…

Date: 2026-05-22

Risk factors for early neurological deterioration in patients with acute ischaemic stroke and assessment of short-term prognosis

Abstract: To identify independent risk factors for early neurological deterioration (END) in patients with acute ischaemic stroke (AIS) and evaluate its impact on short-term…

Date: 2026-05-22

Magnetic resonance imaging and clinical prediction of intracranial atherosclerotic large vessel occlusion in acute ischemic stroke treated with endovascular thrombectomy

Abstract: Intracranial atherosclerosis-related large-vessel occlusion (ICAS-LVO) poses specific challenges during endovascular thrombectomy, and its early identification is…

Date: 2026-05-22

Endovascular thrombectomy in patients with acute ischemic stroke and prestroke mRS 3: a multicenter IPTW analysis focused on functional preservation

Abstract: Evidence for reperfusion therapy in patients with acute ischemic stroke and prestroke disability remains limited because individuals with prestroke modified Rankin Scale…

Date: 2026-05-22