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Automated dose-gradient curve and dose-volume histogram analysis platform: development, validation, and clinical decision support with TG-119 datasets

Abstract: Highly conformal radiotherapy techniques, such as stereotactic radiosurgery and stereotactic ablative radiotherapy, require steep dose fall-off to spare organs at risk…

Date: 2026-05-20

Hepatic arterial infusion chemotherapy plus tyrosine kinase inhibitors with or without PD-1 inhibitors for advanced hepatocellular carcinoma with VP4 portal vein tumor thrombosis: a retrospective cohort study

Abstract: Hepatocellular carcinoma (HCC) with VP4 portal vein tumor thrombosis (PVTT) has a poor prognosis. Although hepatic arterial infusion chemotherapy (HAIC) combined with…

Date: 2026-05-20

Precise radiation, better airway preservation: vocal cord-only image-guided intensity-modulated radiation therapy for early-stage glottic cancer

Abstract: Radiotherapy (RT) achieves excellent local control (LC) in early-stage glottic cancer (ESGC); however, treatment-related edema or necrosis may necessitate tracheostomy…

Date: 2026-05-20

PLAG1 rearrangement may be an oncogenic driver in a subset of sporadic cardiac myxomas: a case–control study

Abstract: Sporadic cardiac myxoma (SCM) is the most common primary tumor of the heart; however, its molecular pathogenesis remains poorly understood. Unlike the familial forms…

Date: 2026-05-20

A prospective risk analysis for the clinical commissioning of a dose-driven continuous scanning proton therapy system

Abstract: Proton dose driven continuous scanning (DDCS) is a form of proton pencil beam scanning (PBS) in which the beam may remain on during transitions between successive spots.…

Date: 2026-05-20

Prognostic value of emotional distress in advanced non–small cell lung cancer: a systematic review and meta-analysis

Abstract: To evaluate the association between emotional distress (ED) and the efficacy of anti-tumor therapies in advanced non-small cell lung cancer (NSCLC). Eligible studies…

Date: 2026-05-20

Mapping local recurrence after radical resection of pancreatic body and tail cancer for target volume design

Abstract: To construct a three-dimensional (3-D) mapping model of local recurrence in patients with pancreatic body and tail cancer (PDTC) after radical resection, and to assess…

Date: 2026-05-20

Seasonal and gender-specific patterns in prescriptions for hypnotic and sedative medications in primary care

Abstract: Population-level prevalence of sleep disorders can be assessed using prescription data for hypnotic and sedative medications. Such prescribing patterns exhibit…

Date: 2026-05-20

Association of CTI and its obesity-related derivatives with incident depression among middle-aged and older adults across CKM stages 0-4: a nationwide prospective cohort study and external clinical validation

Abstract: Cardiovascular-kidney-metabolic (CKM) syndrome integrates metabolic, renal, and cardiovascular risks. While C-reactive protein-triglycerides-glucose (CTI)-related…

Date: 2026-05-20

Linking atrial fibrillation to cerebral small vessel disease: a cross-sectional study with predictive analytics

Abstract: Atrial fibrillation (AF) and cerebral small vessel disease (CSVD) are prevalent in older adults and may synergistically contribute to cognitive decline and stroke risk.…

Date: 2026-05-20