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Development and external validation of an interpretable machine learning model for diagnosing coronary heart disease in patients with type 2 diabetes and MASLD

Abstract: Patients with type 2 diabetes mellitus (T2DM) and metabolic dysfunction-associated steatotic liver disease (MASLD) face substantially elevated coronary heart disease…

Date: 2026-05-15

Non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio is associated with cardiovascular outcomes after percutaneous coronary intervention in patients with type 2 diabetes

Abstract: The non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) is a novel, reliable indicator of dyslipidemia. However, its…

Date: 2026-05-15

Real-world effectiveness and safety of 200 mg abrocitinib initiation in Chinese adults with moderate-to-severe atopic dermatitis: a retrospective study

Abstract: Abrocitinib, a Janus kinase (JAK) inhibitor approved for moderate-to-severe atopic dermatitis (AD), has demonstrated efficacy at 100 mg in randomized controlled trials.…

Date: 2026-05-15

A model combining deep learning and ensemble learning for melanoma recognition via dermoscopy

Abstract: Accurate identification of melanoma is key to improving prognosis, while traditional dermatoscopic recognition suffers from subjectivity and poor consistency. This study…

Date: 2026-05-15

Clinical utility of a host-protein test for suspected infection in the pediatric emergency department: a pragmatic pre-/post-implementation study

Abstract: Identifying infectious etiology in pediatric emergency medicine can be challenging, often leading to antibiotic misuse. MeMed BV (MMBV) is a host-protein test that…

Date: 2026-05-15

Clinical features and risk factors of plastic bronchitis in Mycoplasma pneumoniae pneumonia children with pulmonary consolidation: a prospective cohort study

Abstract: To explore the clinical features and predictive factors of plastic bronchitis (PB) in children with Mycoplasma pneumoniae pneumonia (MPP) and pulmonary consolidation.…

Date: 2026-05-15

A LASSO-based nomogram for predicting acute bilirubin encephalopathy in newborns with severe hyperbilirubinemia

Abstract: To develop and validate a nomogram for predicting acute bilirubin encephalopathy (ABE) in newborns with severe hyperbilirubinemia. A retrospective analysis was conducted…

Date: 2026-05-15

Comparative immunogenicity of COVID-19 vaccination in pregnant and non-pregnant women: a real-world cohort study

Abstract: Pregnant individuals are at increased risk of severe COVID-19-related morbidity and adverse obstetric outcomes, highlighting the importance of effective vaccination.…

Date: 2026-05-15

Genetic analysis of F8 mutations in five hemophilia a carriers

Abstract: Hemophilia A (HA) is an X-linked recessive bleeding disorder caused by mutations in the F8 gene, which exhibits complex molecular mechanisms and high genetic…

Date: 2026-05-15

Lipid metabolism-based machine learning models for predicting large for gestational age in non-diabetic pregnancies

Abstract: The majority of LGA occurs in normoglycemic pregnancies, yet prediction models integrating lipid metabolism for this population are lacking. This study aimed to develop…

Date: 2026-05-15