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Preliminary exploration of the optimal timing of chemoimmunotherapy combined with radiotherapy for oligometastatic esophageal squamous cell carcinoma and analysis of prognostic factors: a multicenter retrospective study

Abstract: To explore the optimal timing of chemoimmunotherapy (CIT) combined with radiotherapy (RT) for oligometastatic esophageal squamous cell carcinoma (ESCC) and analyze…

Date: 2026-05-18

Trajectory changes of symptom clusters in patients with concurrent chemoradiotherapy for cervical cancer: a prospective longitudinal study

Abstract: To identify the trajectory changes of symptom clusters during concurrent chemoradiotherapy in cervical cancer patients and to explore the heterogeneity of symptom…

Date: 2026-05-18

A novel explainable AI for revealing determinants of cancer drug response through integrative multi-omics analysis

Abstract: Cancer drug response rates differ across patients and cell lines; however, many current computational prediction models still function as uninterpretable black boxes,…

Date: 2026-05-18

Neoadjuvant FinHer regimen in patients with HER2-positive breast cancer: a retrospective audit

Abstract: The role of trastuzumab in the neoadjuvant setting has been established by multiple large randomized trials. However, there are limited data on the efficacy and survival…

Date: 2026-05-18

A novel nutritional index for predicting stroke-heart syndrome and clinical outcomes after endovascular treatment

Abstract: Metabolic-nutritional reserves influence stroke outcomes, but their role in large vessel occlusion acute ischemic stroke (LVO-AIS) treated with endovascular thrombectomy…

Date: 2026-05-18

Complete revascularization and heart failure risk in acute coronary syndrome across the ejection fraction spectrum: focus on LVEF-dependent effects

Abstract: To investigate the impact of complete revascularization (CR) versus incomplete revascularization (ICR) on the composite outcome of first hospitalization for heart…

Date: 2026-05-18

Association of the single-point insulin sensitivity estimator with arterial stiffness: a cross-sectional analysis

Abstract: Arterial stiffness is an early marker of vascular damage and cardiovascular risk. SPISE is a simple insulin-free surrogate of insulin sensitivity, but its association…

Date: 2026-05-18

Associations of novel visceral obesity indices (METS-VF and BRI) with dementia: the role of metabolic mediators and genetic susceptibility

Abstract: Visceral obesity-related indices may capture metabolically adverse adiposity more effectively than conventional obesity measures, but their comparative associations with…

Date: 2026-05-18

Association of systemic inflammation response index and triglyceride-glucose index with the severity of coronary artery stenosis in elderly patients: a retrospective cross-sectional study

Abstract: Atherosclerosis is significantly influenced by chronic inflammation and insulin resistance (IR). This study aims to explore the effects of the Systemic Inflammation…

Date: 2026-05-18

Development and application of an evidence-based three-dimensional, four-phase discharge preparation plan for type 2 diabetes patients

Abstract: To develop an evidence-based “three-dimensional integrated” four-stage discharge preparation plan for patients with type 2 diabetes mellitus (T2DM), and to investigate…

Date: 2026-05-15