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Current status of vision and refractive errors among children and adolescents in northeast Sichuan, China: a school-based cross-sectional study

Abstract: To investigate the status of visual acuity and refractive errors among children and adolescents in northeastern Sichuan, providing a basis for targeted myopia prevention…

Date: 2026-05-13

From risk factors to molecular targets: clinical associations and molecular docking insights into phthalate-associated diabetic retinopathy

Abstract: This study aimed to identify novel risk factors for diabetic retinopathy (DR) and to explore whether phthalate exposure contribute to DR pathogenesis. We analyzed data…

Date: 2026-05-13

Clinical efficacy analysis of platelet-rich plasma combined with Xianling Gubao Capsules in the treatment of early-middle stage knee osteoarthritis

Abstract: To assess the clinical efficacy of platelet-rich plasma (PRP) combined with Xianling Gubao Capsules in the treatment of early to moderate knee osteoarthritis (KOA,…

Date: 2026-05-13

Dynamic changes in peripheral blood lymphocyte subsets predict the efficacy and prognosis of immune checkpoint inhibitors in metastatic osteosarcoma

Abstract: Osteosarcoma (OSA) remains the most common primary malignant bone tumor in children and adolescents, with a poor prognosis for metastatic disease. While immune…

Date: 2026-05-13

Rice body synovitis in children: a retrospective study of 6 cases and a systematic literature review of the last two decades (2006–2026)

Abstract: Rice body synovitis (RBS), historically linked to tuberculosis, is increasingly recognized as an articular manifestation of autoimmune diseases in children, particularly…

Date: 2026-05-13

Predictive model for in-hospital acute cerebral infarction in patients with acute gastrointestinal bleeding: a retrospective cohort study

Abstract: Acute gastrointestinal bleeding (GIB) is a common emergency in gastroenterology and may be accompanied by blood loss, anemia, systemic inflammation, and hemodynamic…

Date: 2026-05-13

Incidence of Clostridium difficile infection and enteric pathogens in children with inflammatory bowel disease presenting with disease exacerbation

Abstract: Pediatric patients with inflammatory bowel disease (IBD) are at increased risk of gastrointestinal infections including Clostridioides difficile infection (CDI), which…

Date: 2026-05-13

A preclinical investigation into the potential associations of geraniin with ulcerative colitis alleviation through integrated multi-omics and in vivo analysis

Abstract: This study aims to investigate the potential molecular mechanisms and alleviating effects of geraniin, a natural polyphenol compound, within a murine model of ulcerative…

Date: 2026-05-13

Disease-specific divergence of inflammatory and metabolic biomarkers in neurocritical neuromuscular disorders

Abstract: Myasthenia gravis (MG) and Guillain–Barré syndrome (GBS) are immune mediated neuromuscular disorders that may require intensive immunotherapy and respiratory support.…

Date: 2026-05-13

Association of steroid regimens and withdrawal with relapse risk in myasthenia gravis: a real-world cohort study

Abstract: Corticosteroids (steroids) are the first-line immunotherapy for myasthenia gravis (MG), but the optimal steroid dosing regimen and effects of discontinuation remain…

Date: 2026-05-13