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Impact of COVID-19 history on the prevalence of coronary slow flow: a comparative study in unstable angina patients

Abstract: This study investigated coronary slow flow (CSF) prevalence in post-COVID-19 patients presenting with unstable angina (UA) and angiographically normal coronary arteries.…

Date: 2026-05-08

Efficacy and safety of finerenone in chronic kidney disease stages 3–4 in diabetic and non-diabetic patients with an eGFR 20–60 mL/min: a prospective cohort study

Abstract: Finerenone, when added to the standard-of-care treatment for chronic kidney disease (CKD), can effectively slow its progression. While previous trials have primarily…

Date: 2026-05-08

Real-world experience with sodium-glucose cotransporter 2 inhibitors in adults with Fontan circulatory failure

Abstract: Patients with Fontan physiology frequently develop Fontan circulatory failure (FCF), but there are no evidence-based pharmacological treatment options. This study…

Date: 2026-05-08

Latent profile analysis of depressive symptoms among Chinese older adults with disabilities and associated factors

Abstract: With population aging in China, the number of older adults with disabilities is increasing, and mental health problems, especially depressive symptoms, have become…

Date: 2026-05-08

Elevated homocysteine associated with higher cardiovascular risk in young patients with myocardial infarction: the role of metabolic phenotypes

Abstract: Premature myocardial infarction (PMI) is increasingly recognized as a metabolic disease, driven by a cluster of dysregulations including insulin resistance and central…

Date: 2026-05-08

AI-driven personalised management platform enhances glycaemic control and remission rates in type 2 diabetes: a quasi-experimental prospective cohort study

Abstract: Although artificial intelligence (AI) technologies show promise in diabetes management, real-world evidence supporting AI-driven personalized care remains limited. We…

Date: 2026-05-07

Hyperinsulinemic hypoglycemia due to pathogenic INSR variants: metabolic signature, phenotypic overlap, and semidominant inheritance

Abstract: Familial hyperinsulinemic hypoglycemia type 5 (HHF5) and type A insulin resistance syndrome (TAIRS) are autosomal dominant disorders caused by heterozygous pathogenic…

Date: 2026-05-07

Smoking-induced HLA-DQA1 overexpression in T cells: a novel pathway in thyroid eye disease development

Abstract: Smoking is an established risk factor for thyroid eye disease (TED), its immunopathological mechanisms remain elusive. This study investigates how smoking exacerbates…

Date: 2026-05-07

Tobacco smoking and occupational hand eczema severity in a North African adult population: a cross-sectional analytical study

Abstract: Hand Eczema (HE) is one of the most common occupational diseases worldwide. Various lifestyle factors have been implicated in HE; however, the influence of tobacco…

Date: 2026-05-07

Illness-related stigma mediates the association between disease severity and dermatology- specific quality of life in chronic inflammatory skin diseases: a structural equation modeling study

Abstract: Chronic inflammatory skin diseases substantially impair health-related quality of life (HRQoL). However, clinical severity alone does not fully account for variability…

Date: 2026-05-07