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Liver involvement in pediatric acute leukemia: subtype differences and complex hepatic injury as a novel marker for AML risk stratification

Abstract: This study aimed to investigate the prevalence, pattern of liver involvement at diagnosis of pediatric acute leukemia, and its associations with clinical features and…

Date: 2026-05-07

Multi-omics integration reveals BPGM downregulation and potential plasma metabolite biomarkers for childhood asthma

Abstract: This study aimed to identify potential diagnostic biomarkers and candidate therapeutic targets through multi-omics integration of peripheral blood transcriptomics and…

Date: 2026-05-07

Impact of physical activity on cognitive function in long COVID patients: a cross-sectional observational study

Abstract: The COVID-19 pandemic has resulted in long-term sequelae known as long COVID, which is often characterized by cognitive dysfunctions that impair quality of life.…

Date: 2026-05-07

Multicenter validation of a machine learning model for predicting intrapartum high fever in parturients receiving labor analgesia

Abstract: Intrapartum high fever (?38.5?°C) is associated with adverse outcomes, but predicting its occurrence in parturients with intrapartum fever remains difficult. We…

Date: 2026-05-07

Effects of dexmedetomidine nasal spray combined with propofol for deep sedation in patients undergoing endoscopic retrograde cholangiopancreatography: a prospective randomized study

Abstract: Endoscopic retrograde cholangiopancreatography (ERCP) requires effective and safe deep sedation. Dexmedetomidine is a promising sedative in painless procedures. This…

Date: 2026-05-07

Dietary and supplemental vitamin D intake and pain interference in adults with chronic spine-related pain: a cross-sectional survey study

Abstract: Chronic spine-related pain is a leading driver of global disability, yet the role of modifiable nutritional factors in relation to functional impairment remains…

Date: 2026-05-07

Identifying clinical features associated with electroconvulsive therapy response in adolescents with major depressive disorder using machine learning

Abstract: Electroconvulsive therapy (ECT) is an effective treatment for adolescent major depressive disorder (MDD), but its efficacy varies. This study utilized machine learning…

Date: 2026-05-07

Teleophthalmology adoption and perceived barriers among Colombian general practitioners: a cross-sectional study

Abstract: Telemedicine has improved access to healthcare, reduced costs, and minimized infection risks, particularly during the COVID-19 pandemic. Teleophthalmology may enhance…

Date: 2026-05-07

Combined flap with Masquelet technique and 3D-printed titanium cage for reconstruction of traumatic composite heel defects: a case report and literature review

Abstract: Open calcaneal fractures accompanied by substantial segmental bone loss and severe soft-tissue damage represent a rare clinical presentation. The intricate anatomy of…

Date: 2026-05-07

Treatment outcomes across curve patterns and severities in adolescent idiopathic scoliosis treated with a pattern-specific CAD-CAM brace

Abstract: Whether treatment outcomes differ according to curve pattern or baseline severity in adolescents with idiopathic scoliosis (AIS) remains a subject of debate. In…

Date: 2026-05-07