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The association between social determinants, lifestyle and metabolic factors and the onset of secondary glenohumeral joint osteoarthritis: a cohort study of adults in the UK

Abstract: Secondary Glenohumeral Joint Osteoarthritis (GJO) is a degenerative condition of non-weight-bearing joints. While age and gender are known risk factors, the role of…

Date: 2026-01-27

Development and evaluation of a machine learning model to predict unplanned readmission risk in patients with ulcerative colitis

Abstract: Ulcerative colitis (UC), a chronic inflammatory bowel disease marked by recurrent flares and remissions, often necessitates repeated hospitalization owing to disease…

Date: 2026-01-27

The predictive potential of surrogate indicators of insulin resistance for type 2 diabetic kidney disease

Abstract: Approximately 40% of patients with diabetes develop diabetic kidney disease (DKD), necessitating renal replacement therapy such as dialysis or transplantation.…

Date: 2026-01-27

Association between early depressive symptoms after stroke and trajectories of functional recovery among patients with acute ischemic stroke: a longitudinal study

Abstract: Depressive symptoms are very common in the acute phase of stroke; however, its impact on distinct functional recovery trajectories in acute ischemic stroke (AIS)…

Date: 2026-01-27

A GPT-reinforced social robot for patient communication: a pilot study

Abstract: Quality healthcare requires effective patient communication. However, lack of personnel and increasing demands on healthcare professionals (HCPs) create a need for…

Date: 2026-01-27

Development and computational analysis of high dimensional spectral flow cytometry data for the resolution of innate lymphoid cells in the mammary tumor microenvironment

Abstract: Spectral flow cytometry has ushered in a new era in immunology. Through the improvement of the resolution of surface and intracellular protein expression, this approach…

Date: 2026-01-27

Accumulation of free nuclei denotes defective phagocytic capacity of macrophages and occurs after infection with Listeria monocytogenes and lymphocytic choriomeningitis virus

Abstract: Efficient phagocytosis of pathogens is a key effector function of the innate immune system. Impaired phagocytic activity can result in uncontrolled pathogen…

Date: 2026-01-27

Gemcitabine-docetaxel therapy in pediatric patients with relapsed or refractory sarcoma: a single-center experience

Abstract: The prognosis for pediatric patients with relapsed or refractory sarcoma remains poor, and standard salvage therapies are lacking. This study evaluated the efficacy and…

Date: 2026-01-26

Validation of blood-based indices associated with sarcopenia for the prediction of pneumonia and delirium in patients with acute withdrawal from excessive alcohol consumption

Abstract: This study aimed to explore the hematology-derived relationship between the blood-based indices associated with sarcopenia including the neutrophil-lymphocyte ratio…

Date: 2026-01-26

The impact of radioligand therapy on prognosis in patients with lung neuroendocrine tumors

Abstract: Evidence on the efficacy and safety of radioligand therapy (RLT) in lung neuroendocrine tumors (LNETs) remains scarce. The limited data available, derived mainly from…

Date: 2026-01-26