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Shenqi compound enhances pancreatic ?-cell secretion by promoting the maturation and transport of insulin secretory vesicles through the NOD1/RIP2 signaling pathway

Abstract: Shenqi compound (SQC) is an effective prescription in Chinese medicine to enhance glucose homeostasis and protect pancreatic cells from high glucose-induced damage.…

Date: 2026-01-26

Humanized anti-CD33 CAR-T cells and antibody-drug conjugates for targeted therapy in acute myeloid leukemia

Abstract: Acute myeloid leukemia (AML) is a malignant disorder originating from myeloid hematopoietic stem and progenitor cells. Despite the availability of current treatment…

Date: 2026-01-26

Global trends and future projections of cervical cancer burden: an integrated analysis of GBD 2021, UN population and WHO HPV vaccination data

Abstract: Cervical cancer remains a leading cause of morbidity and mortality among women, disproportionately affecting low- and middle-income countries (LMICs). We sought to: (1)…

Date: 2026-01-26

The role of satisfaction with care among factors affecting health-related quality of life in people with cancer: a cross-sectional study

Abstract: Despite advances in therapies that have increased the duration of post-diagnosis survival, living with long-term adverse effects of cancer and its treatment is common.…

Date: 2026-01-26

Gender-specific motivation for training in sexual history

Abstract: Although sexual history taking is an essential component of a comprehensive medical history, it is often omitted in practice. To ensure competent assessment, this skill…

Date: 2026-01-26

Combining 3D printing technology with customized metal plates for the treatment of long segment femoral shaft comminuted fractures

Abstract: This study aims to evaluate the clinical value of combining 3D printing technology with customized metal plates in the treatment of long-segment femoral shaft comminuted…

Date: 2026-01-26

Area-to-Length Ratio: a significant predictor of nonunion following intramedullary nailing of comminuted femoral shaft fractures

Abstract: The relationship between fragment characteristics and nonunion risk in comminuted femoral shaft fractures remains controversial. This study aimed to investigate the…

Date: 2026-01-26

The efficacy and safety of endoscopy-assisted anterior cervical discectomy and fusion for the treatment of cervical spondylotic myelopathy

Abstract: The aim of this study was to describe the surgical technique of endoscopy-assisted anterior cervical discectomy and fusion (ACDF), to evaluate the advantages, efficacy,…

Date: 2026-01-26

Molecular crosstalk between MASLD and IVDD revealed through integrated biomarker discovery analysis

Abstract: Non-alcoholic fatty liver disease (NAFLD), recently retermed as metabolic dysfunction-associated steatotic liver disease (MASLD), and intervertebral disc degeneration…

Date: 2026-01-26

Correlation between sagittal and inclined angles of cervical facet joints and cervical disc herniation: a radiological observational study

Abstract: Previous studies have found that asymmetry of cervical facet joints is associated with cervical disc herniation. However, the effect of facet joint angle on disc…

Date: 2026-01-26