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Beyond mean heart dose: differentiated electrocardiographic manifestations and dosimetric mechanisms of cardiac injury in left-sided versus right-sided breast cancer after intensity-modulated radiotherapy

Abstract: To investigate dosimetric exposure variations to the whole heart and substructures between left- and right-sided breast cancer patients receiving intensity-modulated…

Date: 2026-09-16

Comparative evaluation of five nutrition-inflammation indices for predicting 28-day ICU mortality in critically ill patients with bone infections: a dual-cohort study with external validation and interpretable machine learning

Abstract: Malnutrition and systemic inflammation are highly prevalent among critically ill patients with bone infections and may independently predict adverse outcomes. Five…

Date: 2026-09-16

Resection margins in transoral oropharyngeal surgery: comparative analysis of robotic and VITOM Eagle–assisted exoscopic approaches

Abstract: Transoral robotic surgery (TORS) is widely regarded as the current benchmark minimally invasive approach for early-stage oropharyngeal squamous cell carcinoma (OPSCC),…

Date: 2026-09-16

Engineered CAR-T extracellular vesicles loaded with miR-17-5p inhibitor suppress hepatocellular carcinoma progression

Abstract: Hepatocellular carcinoma (HCC) immune escape is co-driven by tumor malignant proliferation and an immunosuppressive tumor microenvironment, characterized by frequently…

Date: 2026-09-16

Integrative multi-omics analysis unveils the regulatory landscape of diabetic cardiomyopathy: from chromatin accessibility to transcript isoforms and epitranscriptome

Abstract: Diabetic cardiomyopathy (DCM) is a major contributor to heart failure in diabetic patients, characterized by profound metabolic remodeling and diastolic dysfunction.…

Date: 2026-09-16

Allogeneic hematopoietic stem cell transplantation is associated with improved survival compared with chemotherapy in patients with acute myeloid leukemia harboring favorable-risk genetic features at initial diagnosis: a single-center retrospective study

Abstract: Acute myeloid leukemia (AML) harboring favorable-risk genetic features at initial diagnosis (FR-AML) commonly achieves remission after chemotherapy, but the optimal…

Date: 2026-09-15

Early-pregnancy BMI-derived adiposity change rate and gestational diabetes mellitus risk: modification by a fatty liver index–defined hepatic-metabolic phenotype

Abstract: Gestational diabetes mellitus (GDM) is commonly diagnosed at 24–28 weeks of gestation; however, metabolic susceptibility that precedes dysglycemia may emerge earlier. We…

Date: 2026-09-15

Identification of risk factors for type 2 diabetes across age-based proxies of early and late postmenopausal stages in prediabetic women

Abstract: Prediabetes is increasingly prevalent, and women transitioning through menopause may face a particularly elevated risk of progressing to type 2 diabetes (T2DM). Estrogen…

Date: 2026-09-15

Clinical, hematologic, and inflammatory factors associated with psoriatic arthritis in a Chinese hospital-based study

Abstract: Psoriatic arthritis (PsA) develops in up to approximately 30% of patients with psoriasis (PsO) and can cause irreversible joint damage. For dermatologists, identifying…

Date: 2026-09-15

Multidimensional neuropsychological heterogeneity in obstructive sleep apnea: deep clinical phenotyping in a single-center cohort, population proteomic context, and depressive-burden risk stratification

Abstract: Obstructive sleep apnea (OSA) is associated with substantial cognitive and affective burden, yet conventional respiratory severity does not fully explain this…

Date: 2026-09-15