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Transcriptomics-based analysis of muscle injury mechanism mediated by inflammatory imbalance in the Duchenne muscular dystrophy muscle microenvironment

Abstract: Duchenne muscular dystrophy (DMD) is a hereditary neuromuscular disease characterized by progressive myofiber injury, chronic inflammatory response, and persistent…

Date: 2026-09-15

Preoperative depressive symptoms as a marker of postoperative delirium risk in older adults: a prospective cohort study in spine surgery

Abstract: Postoperative delirium (POD) is a frequent perioperative complication in older adults and is associated with delayed recovery and adverse cognitive outcomes. We…

Date: 2026-09-15

Long-term mental health and quality of life in patients after cervical artery dissection

Abstract: Most patients with Cervical Artery Dissection (CeAD) experience good long-term functional outcome. Little is known about long-term psychological sequelae in these…

Date: 2026-09-15

Gray matter atrophy mediates the association between cerebral hypometabolism and cognitive impairment in Alzheimer’s disease

Abstract: Alzheimer’s disease (AD) is characterized by amyloid deposition, brain hypometabolism, gray matter atrophy and cognitive decline, yet their causal interactions are…

Date: 2026-09-15

A systems-level analysis of global gene expression in resistant and susceptible Biomphalaria glabrata in response to Schistosoma mansoni infection

Abstract: The freshwater gastropod Biomphalaria glabrata is the major intermediate host of Schistosoma mansoni , the causative agent of human schistosomiasis. Elucidating the…

Date: 2026-09-15

Immunosuppression as an associated risk factor for high-grade cervical lesions: a comparative study of cytology, HPV, and histopathology

Abstract: Persistent high-risk human papillomavirus (hrHPV) infection is the main cause of cervical carcinogenesis, and impaired immune surveillance may increase the risk of viral…

Date: 2026-09-15

Impact of molecular profiling in patients with endometrial cancer: real world experience from India

Abstract: The introduction of The Cancer Genome Atlas (TCGA) had made a paradigm shift towards molecular based classification that impacted the treatment of endometrial cancer…

Date: 2026-09-15

Efficacy and safety analysis of induction therapy for unresectable locally advanced non-small-cell lung cancer: a retrospective study based on IPTW

Abstract: Concurrent chemoradiotherapy (cCRT) followed by consolidation immunotherapy constitutes the current standard of care for unresectable locally advanced non–small cell…

Date: 2026-09-15

Transcriptomics, identification, and testing of manganese metabolism-related genes in cervical squamous cell carcinoma

Abstract: Cervical squamous cell carcinoma (CSCC) remains a leading cause of cancer-related mortality in women, and few effective prognostic biomarkers have been identified.…

Date: 2026-09-15

Integration of MRI radiomics with immune profiling to predict response to CDK6 inhibitors in high-grade glioma

Abstract: Predictive biomarkers are needed to identify patients with high-grade glioma who benefit from cyclin-dependent kinase 6 (CDK6) inhibition. We hypothesized that an…

Date: 2026-09-15