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Impact of ALC Nadir and EDRIC on survival outcomes in limited-stage small cell lung cancer receiving chemoradiotherapy: a retrospective analysis comparing twice-daily and once-daily radiotherapy

Abstract: This study aimed to evaluate the prognostic value of absolute lymphocyte count (ALC) nadir and estimated dose of radiation to immune cells (EDRIC) in patients with…

Date: 2026-09-15

Impaired antigen clearance of macrophages associates with heart failure and non-obstructive azoospermia: insights from transcriptomics, in silico knockout, and in vitro validation

Abstract: Heart failure (HF) and non-obstructive azoospermia (NOA) are high-burden diseases that share chronic inflammation and tissue injury. Macrophages are key regulators in…

Date: 2026-09-15

Prognostic value of soluble ST2 in cardiac magnetic resonance defined myocardial infarction with non-obstructive coronary arteries

Abstract: Cardiac magnetic resonance (CMR) plays an essential role in identifying the underlying etiology of myocardial infarction with non-obstructive coronary arteries (MINOCA).…

Date: 2026-09-15

Latent profiles and transitions of acute psychological stress in patients with acute myocardial infarction after percutaneous coronary intervention and their association with cardiac rehabilitation participation

Abstract: To explore the dynamic transitions of latent profiles of acute psychological stress in patients with acute myocardial infarction across three time points and their…

Date: 2026-09-15

Four months of DHA and whey protein supplementation in semi-professional female soccer players: a prospective non-randomized controlled study of omega-3 status, hematological outcomes, and physical performance

Abstract: Omega-3 polyunsaturated fatty acids (n-3 PUFAs) are well established in cardiovascular and cognitive health, yet their role in athletic performance remains…

Date: 2026-09-14

Assessment of minimum discard volume for central venous catheter sampling: Validation via busulfan therapeutic drug monitoring in pediatric transplant patients

Abstract: Frequent blood sampling in pediatric patients, particularly during hematopoietic stem cell transplantation (HSCT), can lead to significant cumulative blood loss and…

Date: 2026-09-14

Diabetes mellitus is an independent risk factor for surgical site infection after orthopedic Class I incision surgery: a retrospective cohort study

Abstract: Surgical site infection (SSI) is one of the most devastating complications following orthopedic Class I incision surgery. Diabetes mellitus (DM) has been implicated as…

Date: 2026-09-14

Tissue-nonspecific alkaline phosphatase deficiency is associated with altered immune cell profiles in hypophosphatasia

Abstract: Hypophosphatasia (HPP) is a rare metabolic disorder caused by mutations in the ALPL gene leading to tissue-nonspecific alkaline phosphatase (TNSALP) deficiency. Although…

Date: 2026-09-14

Astragalus polysaccharide antagonized anti PD-1 efficacy in melanoma through inhibiting JAK-STAT1/CIITA and TLR/NF-?B signaling

Abstract: Advanced melanoma remains a major clinical challenge due to resistance to immune checkpoint inhibitors (ICIs, e.g., anti PD-1). Astragalus Polysaccharide (APS) is a…

Date: 2026-09-14

Association of the inflammation indicators with multiple system involved of immunoglobulin A vasculitis in children

Abstract: Immunoglobulin A vasculitis (IgAV) is the most common childhood vasculitis, and involvement of multiple systems (gastrointestinal, joint, renal) may affect prognosis.…

Date: 2026-09-14