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Circadian disruption and circulating TGF-?1 in workers: evidence from Mendelian randomization and observational data

Abstract: Circadian disruption is increasingly recognized as an important biological stressor underlying chronic disease, yet its direct immunological effects remain unclear.…

Date: 2026-09-10

Flow in screen-based gamified virtual reality sports: development and validation of a behaviorally anchored proxy rating scale for adolescents with autism spectrum disorder

Abstract: Adolescents with autism spectrum disorder (ASD) face substantial barriers to physical activity participation because of motor coordination difficulties, sensory…

Date: 2026-09-10

Sex differences in leptin levels but not in the leptin response to sacubitril/valsartan in patients with heart failure with reduced ejection fraction

Abstract: Leptin is an adipokine involved in metabolic regulation and neurohormonal activation and has been implicated in the pathophysiology of heart failure.…

Date: 2026-09-10

Assessment of medical and dental students' knowledge, attitudes and practices related to fluoride exposure: a cross-sectional study from Jordan

Abstract: Fluoride is protective against dental caries, but chronic overexposure causes dental and skeletal fluorosis and has been associated with neurological, endocrine, and…

Date: 2026-09-10

Psychometric evaluation of a multidimensional family resource assessment tool for schizophrenia (M-FRAT) from caregivers’ perspectives in communities of Beijing, China

Abstract: A standardized and comprehensive instrument specifically designed to evaluate the support needs of families affected by schizophrenia is needed. This study aimed to…

Date: 2026-09-10

Clinicopathological characteristics and factors associated with axillary lymph node metastasis in multifocal/multicentric versus unifocal breast cancer: a retrospective study

Abstract: Multifocal/multicentric breast cancer (MMBC) may exhibit a greater tumor burden and higher risk of lymph node involvement than unifocal breast cancer (UFBC). This study…

Date: 2026-09-10

A comparative study of wound healing kinetics, efficacy, and profiling of VG111 in canine wounds

Abstract: The management of naturally occurring canine wounds, such as bite and degloving injuries, remains a major veterinary challenge because standard treatments often struggle…

Date: 2026-09-10

Ukrainians under continuous traumatic stress: towards increasing the diagnostic condition’s clinical utility

Abstract: The World Health Organization would include a diagnosis of Continuous Traumatic Stress (ConTS) Reaction or Disorder in its ICD-11 classification system if there were…

Date: 2026-09-10

Development and validation of an interpretable machine learning model for early prediction of postoperative atrial fibrillation following on-pump cardiac surgery

Abstract: Postoperative atrial fibrillation (POAF) complicates 20%–40% of cardiac surgeries, increasing morbidity, length of stay, and healthcare costs. Early risk stratification…

Date: 2026-09-10

An empirical study of diagnosis-related group classification for hospitalization costs in lumbar disk herniation patients treated in Chinese medicine hospitals in China

Abstract: Lumbar disk herniation (LDH) is a frequent and multiple disease that imposes a heavier global economic burden. As China’s diagnosis related group (DRG) payment system…

Date: 2026-09-10