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Preoperative HALP and LMR predict disease-free survival in stage III colon cancer and enable nomogram-based risk stratification

Abstract: Colorectal cancer remains a major cause of cancer-related mortality worldwide. Despite curative resection and standard adjuvant chemotherapy, patients with stage III…

Date: 2026-04-29

Construction and verification of 5-year survival prediction model for post-op ESCC patients

Abstract: To develop a predictive model for the 5-year postoperative survival rate of patients with esophageal squamous cell carcinoma (ESCC), and to provide a basis for the…

Date: 2026-04-29

Association of SPISE with prevalent and incident MASLD: a two-stage population-based study and development of a risk prediction model

Abstract: The prevalence of metabolic dysfunction–associated steatotic liver disease (MASLD) is increasing, and the disease is often asymptomatic in its early stages. Insulin…

Date: 2026-04-29

Ancestry-informative markers and variants of uncertain significance on hereditary cancer panels

Abstract: Variants of uncertain significance (VUS) on multigene cancer panels can increase patient anxiety and lead to unnecessary interventions. Prior literature shows that,…

Date: 2026-04-29

Prognosis and risk factors for pathological non-response to neoadjuvant chemoimmunotherapy in locally advanced esophageal squamous cell carcinoma

Abstract: Neoadjuvant chemotherapy combined with immunotherapy (NACI) is promising for treating locally advanced esophageal squamous cell carcinoma (LA-ESCC), yet a subset of…

Date: 2026-04-29

The knowledge, attitude, and practice score on oral nutrition supplementation is inversely associated with malnutrition risk of tumor patients during the peri-radiotherapy period: a multicenter cross-sectional study

Abstract: Oral nutritional supplements (ONS) plays a key role in improving outcomes in cancer patients undergoing radiotherapy. However, the relationship between patients’…

Date: 2026-04-29

The survival impact of upfront or sequential chemoradiotherapy in locally advanced esophageal squamous cell carcinoma

Abstract: The treatment of locally advanced unresectable esophageal squamous cell carcinoma (ESCC) is a clinical challenge with limited therapeutic consensus. The immune…

Date: 2026-04-29

Distinct protein and metabolic profiles in patients with advanced clear-cell renal cell carcinoma treated with sunitinib: a study of the Spanish oncology genitourinary group

Abstract: New biomarkers are needed to improve treatment selection in patients with metastatic clear cell renal cell carcinoma (CCRCC). This study aims to identify predictive…

Date: 2026-04-29

Circulating CTRP9 and aortic valve calcification jointly predict coronary artery calcification in coronary heart disease patients

Abstract: Vascular calcification predicts adverse cardiovascular outcomes. CTRP9, an adiponectin paralog, has vascular protective effects. We evaluated the association of…

Date: 2026-04-29

Systemic inflammatory response drives post-cardiac arrest multi-organ injury via IL-17 signaling in murine and porcine models

Abstract: Systemic inflammation plays a central role in the development of multi-organ diseases. Post-cardiac arrest syndrome (PCAS) is increasingly recognized as a systemic…

Date: 2026-04-29