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Paeoniflorin prevents acute graft-versus-host disease while preserving graft-versus-tumor effects

Abstract: Acute graft-versus-host disease (aGVHD) remains a major complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT). This study investigated the…

Date: 2026-09-08

Hematologic response assessment in monoclonal gammopathy of renal significance: critical appraisal of current criteria

Abstract: Current recommendations for hematologic response (HemR) assessment in monoclonal gammopathies of renal significance (MGRS) are based on the monoclonal immunoglobulin…

Date: 2026-09-08

Increased interleukin-8 levels in cord blood serum of newborn—possible effect of cytokine dysregulation in pregnancies complicated by rheumatic disease on newborn vasculature

Abstract: Systemic autoimmune rheumatic diseases (SARDs) are associated with a higher risk of cardiovascular diseases. During pregnancy, maternal immune disbalance might impact…

Date: 2026-09-08

Comparative screening performance and multicenter validation of novel inflammatory biomarkers (NLR, SII, and CAR) for risk stratification of diabetic foot ulcer in patients with type 2 diabetes mellitus

Abstract: To compare the screening performance of the neutrophil-to-lymphocyte ratio (NLR), systemic immune-inflammation index (SII), and C-reactive protein-to-albumin ratio (CAR)…

Date: 2026-09-08

Serum 11-ketotestosterone is associated with overall disease-control status but adds limited information beyond androstenedione in children with 21-hydroxylase deficiency

Abstract: Monitoring children with 21-hydroxylase deficiency (21-OHD) requires suppression of adrenal androgen excess while avoiding glucocorticoid overtreatment. However, the…

Date: 2026-09-08

Evaluation of dermatological asymmetry measure of shape by histogram energy measure

Abstract: This study addresses automatic detection of skin changes especially asymmetry and symmetry of the lesions and their crucial role in the definition of dermatological…

Date: 2026-09-08

Association between severity of different body regions and inadequate control of atopic dermatitis: results from a cross-sectional and longitudinal study

Abstract: The Atopic Dermatitis Control Tool (ADCT) serves as a key metric for assessing atopic dermatitis (AD) management. However, the relationship between eczema severity in…

Date: 2026-09-08

PLAU promotes fibroblast activation and keloid fibrogenesis through PLAUR–Dependent TGF–?/Smad signaling

Abstract: Keloids are fibroproliferative disorders conditions of the dermis with dysregulated immune responses contributing to disease progression. However, the causal…

Date: 2026-09-08

Clinical spectrum of pediatric histoplasmosis in Mexico: description of seven cases and literature review

Abstract: Histoplasmosis is a systemic mycosis caused by the dimorphic fungus Histoplasma capsulatum (H.capsulatum) . It represents a diagnostic challenge in the pediatric…

Date: 2026-09-08

LLM and CQL computable phenotypes for myocarditis adverse event feature and outcome determinations using patient FHIR data: a feasibility study

Abstract: Post-market surveillance for adverse events of special interest is often constrained by key diagnostic elements being captured primarily in unstructured clinical notes…

Date: 2026-09-08